A discussion of the physical principles governing biomolecular structure and function. CHEM 114A. CHEM 104. Restricted to first-year and sophomore enrollment. Topics include quantum mechanics, molecular structure, spectroscopy fundamentals and applications to biomolecules, optical spectroscopy, NMR, and statistical approaches to protein folding. Special Study in Chemistry (112).
Students may not receive credit for CHEM 132 and either CHEM 126A or CHEM 127. Course covers basics of X-ray diffraction, instrumentation for diffraction data collection, crystalline habits and space group symmetry and introduction to the software required for data acquisition, structure solution, refinement.Prerequisites: graduate standing. (May not be offered every year.). Nonequilibrium systems: glasses, transport, time correlation functions, Onsager relations, fluctuation-dissipation theorem, random walks, Brownian motion. May be taken for credit up to four times, with a change in topic, and permission of the department. CHEM 130. Advanced Inorganic Chemistry Laboratory (4). Introduction to Teaching Science (2). The course will focus on the development and analysis of submicroscopic models of matter and structure-property relationships to explain, predict, and control chemical behavior. Prerequisites: CHEM 6B or CHEM 6BH. (May not be offered every year. Under the supervision and mentorship of a course instructor, MS and PhD students serve as teaching assistants to undergraduate laboratory and lecture courses. This course is an introduction to the metabolic reactions in the cell which produce and utilize energy. Selected topics in RNA structure and function, such as the ribosome, ribozyme, antibiotics, splicing and RNA interference, as they relate to the RNA role in gene expression and regulation. CHEM 151. Objectives include learning rules, issues, and resources for research ethics; and understanding the value of ethical decision-making. An introduction to teaching chemistry. Honors Organic Chemistry I (4). A survey of the biochemical action of drugs and toxins as well as their absorption and excretion. The course content is built on a background in mathematics and physical chemistry, and provides an introduction to computational theory and molecular mechanics. An introduction to chemical concerns in nature with emphasis on soil and water issues like agricultural productivity, biological impacts in the environment, deforestation, ocean desserts, natural and manmade disasters (fires, nuclear winter, volcanoes), and waste handling. Recommended as the first course of the sequence. Continuation of CHEM 40A, Organic Chemistry I. With CHEM 130 and 131, CHEM 132 is part of the Physical Chemistry sequence taught over three quarters. A survey of this field from a synthetic and mechanistic viewpoint. Methods of Teaching Chemistry (4). A continuation of the discussion of structure, bonding, and reactivity with emphasis on transition metals and other elements using filled d orbitals to form bonds. Seminar in Inorganic Chemistry (2). Continuation of Organic Chemistry 40B or 40BH, at honors level. Chemical Physics: Stat Thermo II (4). May be coscheduled with CHEM 115. CHEM 242. May be coscheduled with CHEM 264. Organic Chemistry Laboratory (4). Emphasis will be given to compounds approved over the last three decades and investigational drugs that are in clinical trials.
(S/U grades only.) (May not be offered every year.) Introduction to Glycosciences (4). ), CHEM 200B. Independent literature or discipline-based education research by arrangement with, and under the direction of, a member of the Department of Chemistry and Biochemistry faculty. Prerequisites: CHEM 126 or 126B or 130 or 133 and MATH 20C or 31BH. Mathematics for Physical Chemistry (4). A broad introduction to the uses of nuclear magnetic resonance to characterize and understand proteins. CHEM 105A. Bioorganic and Natural Products Chemistry (4). Program or materials fees may apply. Renumbered from CHEM 140C.
Laboratory course in experimental physical chemistry. Introduction to Glycosciences (4). Experimental methods and techniques involved in chemical research are introduced.
Teaching Methods in Chemistry and Biochemistry (2). UC San Diego 9500 Gilman Dr. La Jolla, CA 92093 (858) 534-2230. Fundamentals of Instrumental Analysis (4), Fundamental theoretical principles, capabilities, applications, and limitations of modern analytical instrumentation used for qualitative and quantitative analysis. Recommended: completion of a high school physics course strongly recommended. Methods of analysis, chemistry of hydrocarbons, chemistry of the carbonyl group. May be coscheduled with CHEM 252. Prerequisites: CHEM 6C or 6CH, and PHYS 2C or 2D, and MATH 20D. Biophysical Chemistry of Macromolecules (4). All rights reserved. The course addresses questions and issues arising from the expected increases in the development of nanotechnology-based consumer products and their potential effects on the environment. Regulatory Circuits in Cells (4).
Students are exposed to the science of teaching in science in actual practice. Prerequisites: MATH 20D. Recommended preparation: CHEM 171 (formerly 149A). CHEM 41B. Recommended: concurrent or prior enrollment in MATH 10B or 20B. Prerequisites: CHEM 6C and PHYS 2C. (S/U grades only.) Students may not receive credit for CHEM 276 and NANO 267. Prerequisites: CHEM 6C or 6CH. Prerequisites: consent of instructor. The course focuses on the discovery and development of modern antibiotics. A survey of inorganic chemistry to prepare for graduate research in the field, including a detailed introduction to nuclear magnetic resonance (NMR), followed by applications of NMR to structural and mechanistic problems in inorganic chemistry. Students completing 6AH may not subsequently take 6A for credit. CHEM 204 students will be required to complete additional paper and/or exam beyond that expected of students in CHEM 104. Students may not receive credit for CHEM 108 and BIBC 103.
A materials fee is required. ), CHEM 271. Prerequisites: MATH 20C and CHEM 126 or CHEM 126B or CHEM 130 or CHEM 133. A discussion of current topics in chemical biology including mechanistic aspects of enzymes and cofactors, use of modified enzymes to alter biochemical pathways, chemical intervention in cellular processes, and natural product discovery. Prerequisites: CHEM 40B or 140B (a grade of C or higher in CHEM 40B or 140B is strongly recommended). Letter grades only. The course is structured around major themes in the field, starting from basic understanding of structure and molecular interactions of carbohydrates, to the mechanisms of their biological functions in normal and disease states, to their applications in materials science and energy generation. ), CHEM 236.
May be coscheduled with CHEM 154. Atmospheric photochemistry, radical reactions, chemical lifetime determinations, acid rain, greenhouse effects, ozone cycle, and evolution are discussed. Our alumni are accepted to the best graduate and professional schools in the country, and have gone on to establish successful scientific careers. May be coscheduled with CHEM 190. Prerequisites: CHEM 40C, 140C, 40CH or 140CH and CHEM 114A. This course will provide an introduction to the physics and chemistry of soft matter, followed by a literature-based critical examination of several ubiquitous classes of organic nanomaterials and their technological applications. (Cross-listed with SIO 141.) Survey of the chemistry of semiconductors, superconductors, molecular magnetic materials, zeolites, fast ion conductors, electronically conducting polymers and ceramics. Students may not receive credit for both CHEM 114A and BIBC 100. (Cross-listed with BENG 276.) Biochemical Energetics and Metabolism (4). Prerequisites: advanced graduate-student standing. This course has two components. Topics include biosynthesis of natural products, molecular recognition, and small molecule-biomolecule interactions. Corequisite: CHEM 109. Synthetic Methods in Organic Chemistry (4). Special Topics in Chemical Physics (2 or 4), Topics of special interest will be presented. Students will learn how to define the nature of an analytical problem and how to select an appropriate analytical method. CHEM 114D. May be coscheduled with CHEM 258.
CHEM 40C and at least one course in either general biology, molecular biology, or cell biology is strongly encouraged. Prerequisites: CHEM 43A, 143A, 43AM, or 143AM and CHEM 114A. May be coscheduled with CHEM 246.
Course in computational methods, with focus on quantum chemistry. Examine theories of learning and how they are important in the science classroom. Introduction to molecular bonding and structure and chemical reactions, including organic molecules and synthetic polymers. (May not be offered ever year.). Topics include carbohydrates, lipids, amino acids and proteins, with an introduction to metabolic pathways in human physiology. Prerequisites: CHEM 105A. CHEM 113. CHEM 100A. Enrollment preference given to chemistry and biochemistry majors, followed by other science/engineering majors. Conceptual development is fostered, as well as continued development of knowledge of science history. ), CHEM 229. The course material will include energy-producing pathways: glycolysis, Krebs cycle, oxidative phosphorylation, fatty-acid oxidation. May be coscheduled with CHEM 254. Even with over 20,000 students enrolled in our classes each year and 1,400+ undergraduate majors, we still provide opportunities for individualized study, mentoring and advising from our faculty and staff. Includes but is not limited to advanced kinetics, advanced spectroscopy, computational chemistry, heterocyclic chemistry, medicinal chemistry, organotransition metal chemistry, polymers, solid-phase synthesis/combinatorial chemistry, stereochemistry, and total synthesis classics. Capstone Seminar in Science Education (4). CHEM 259. CHEM 298. Students are required to attend a weekly class on methods of teaching chemistry and will teach a discussion section of one of the lower-division chemistry courses. Separation, purification, spectroscopy, product analysis, and effects of reaction conditions. May not be taken for credit after CHEM 6AH. Prerequisites: graduate standing or consent of instructor. A chemical perspective of the origin and evolution of the biogeochemical systems of stars, elements, and planets through time. (May not be offered every year. CHEM 195. Similar to CHEM 40B but emphasizes mechanistic aspects of reactions and effects of molecular structure on reactivity. Prerequisites: CHEM 114A. Organic chemistry laboratory for chemistry majors; nonmajors with strong background in CHEM 40A or 140A may also enroll, though preference will be given to majors.
May be coscheduled with CHEM 185. Mechanisms of Organic Reactions (4). General Chemistry Laboratory (4). The course is a rigorous and in-depth study of fundamental organic chemistry with an introduction to chemical reactivity and synthesis, Bonding theory, structure (including isomerism, stereochemistry, conformations) and physical properties of carbon-containing molecules. (May not be offered every year.). The aim of this course is to develop an appreciation for a variety of topics in signal transduction. Restricted to the following major codes: CH25, CH31, CH34, CH35, CH36, CH37. Prerequisites: graduate standing. Prerequisites: biochemistry background and graduate standing, or approval of instructor. Fundamental reactivity patterns for transition element organometallic compounds will be discussed and organized according to periodic trends. Prerequisites: graduate standing. Continuation of theoretical quantum mechanics: evolution operators and time dependent representations, second quantization, Born-Oppenheimer approximation, electronic structure methods, selected topics from among density operators, quantized radiation fields, path integral methods, scattering theory. Topics include thermodynamics, first and second laws, chemical equilibrium, solutions, kinetic theory, enzyme kinetics. Lecture focuses on fundamental theoretical principles, applications, and limitations of instrumentation used for qualitative and quantitative analysis. Prerequisites: graduate standing and department approval required. Students may not receive credit for both CHEM 100B and 101. CHEM 214. May be coscheduled with CHEM 256. Foundations of polymeric materials. Prerequisites: CHEM 43A, 143A, 43AM or 143AM, and CHEM 40B or 140B. Organic Chemistry III: Synthesis, Reactivity, and Macromolecules (4). Focus on select topics from among numerous areas relevant to chemistry, including linear algebra, probability theory, group theory, complex variables, Laplace and Fourier transforms, partial differential equations, stochastic variables, random walks, and others. Intended for nonscience majors. (Cross-listed with EDS 31.) Also included are metal complexes in medicine, toxicity, and metal ion storage and transport. (S/U grades only.) Prerequisites: CHEM 6B or CHEM 6BH. The topics emphasized will vary from year to year. Topics include colligative properties, bulk material properties, chemical equilibrium, acids and bases, and thermodynamics.