xS**T0T0 Bi yA$ [zUwo[]j_E`C #7.hh!9[Ib
-aN_h]An'$x\iCON!pdD:-uDC|^;v^6_xA4o@u_Tu`?Mlmv=-tm6Xkt\7bv5==w\Cp]|q 'ZO,. Our results remained consistent after we excluded the seven patients with a mean flow velocity exceeding 140 cm/s at MCA, which indicates an asymptomatic artery stenosis of 50% or more.18 Similar results were also observed when heart rate and mean arterial pressure on 24-h ambulatory measurement in the multivariate models were replaced by that of office measurement (data not shown). Mages S, Hensel O, Zierz A, Kraya T, Zierz S. Experimental provocation of ice-cream headache by ice cubes and ice water. (2012) 26:6854. endobj x%05Qk!Fj )=S!oo7~7!`4,R55d]C|O3C#5d8>L The increase in the PI for a 1-s.d. The increase in MFV was more pronounced in volunteers with provoked HICS than in volunteers without HICS. Cardiovascular responses to water drinking: does osmolality play a role? ba-PWV was a slightly stronger correlate of the PI in the MCA than cf-PWV, probably because the travel path to compute ba-PWV involves both elastic and muscular arteries, whereas cf-PWV reflects only stiffness of the central elastic arteries. Ages ranged between 18 and 60 years (mean age 26.5 7.7 years; 47/77 women). Cephalalgia. Arterial stiffening of the large arteries as measured by PWV is a risk factor for cerebrovascular disease probably because it increases the pulsatile component of blood pressure, which is transmitted to the cerebral capillaries. 2005 May;24(5):697-702. doi: 10.7863/jum.2005.24.5.697. Pulse wave travel distance was calculated as distance B minus distance A. Pulse transit time was the average of 10 consecutive beats. <>stream 4.Laurent S, Katsahian S, Fassot C, Tropeano AI, Gautier I, Laloux B, Boutouyrie P. 5.Brandts A, van Elderen SG, Westenberg JJ, van der Grond J, van Buchem MA, Huisman MV, Kroft LJ, Tamsma JT, de Roos A. The five arterial stiffness indices were intercorrelated (r 0.37; P < 0.001). We performed the ShapiroWilk test and DurbinWatson test to check the normality and independence of the residuals in the linear regressions, respectively. Middle cerebral artery peak systolic velocity: is it the standard of care for the diagnosis of fetal anemia?
27.Paulson OB, Waldemar G, Schmidt JF, Strandgaard S. 28.Hirata K, Yaginuma T, O'Rourke MF, Kawakami M. 29.Kelly R, Hayward C, Avolio A, O'Rourke M. Oxford University Press is a department of the University of Oxford. 3 0 obj The variance of PI was mainly explained by pulse pressure measures (3967% of total variance), and was very little explained by ba-PWV (5%). These observations suggest that brain arteries are subjected to high pulsatile circumferential stress and high longitudinal shear stress. No use, distribution or reproduction is permitted which does not comply with these terms. For database management and statistical analyses, we used the SAS software, version 9.1.3 (SAS Institute, Cary, NC). (2012) 32:112330.
University of Erlangen Nuremberg, Germany, Faculty of Medicine, Okan University, Turkey. 1 PWV was the distance in meters divided by the transit time in seconds. 6.Maldonado J, Pereira T, Polnia J, Silva JA, Morais J, Marques M. 7.Kim DH, Choi JH, Moon JS, Kim HJ, Cha JK. Forehead stimulation decreases volume of the infarction triggered by permanent occlusion of middle cerebral artery in rats. FASEB J. In a further step of the analysis, we constructed a model including both bPP and ba-PWV in addition to the covariables. endstream The cold stimulation of the trigeminal nerve might also activate the sympathetic system, which causes peripheral vasoconstriction, a lowering of skin temperature (8) and increase in MAP (9). Within 1 week before the arterial examinations, the patients underwent 24-h ambulatory blood pressure monitoring. Few studies addressed the relation between the flow pattern in cerebral artery and arterial stiffness in the systemic circulation. The correlations between the PI and brain lesions were 0.52 (P < 0.001) for periventricular hyperintensity, 0.54 (P < 0.001) for deep white matter hyperintensity and 0.31 (P = 0.02) for lacunar disease. From March 2009 to January 2011, we invited 791 consecutive patients who were not on antihypertensive medications for at least 2 weeks and were referred for ambulatory blood pressure monitoring to the Hypertension Clinic of Ruijin Hospital, Shanghai, China. Cephalalgia. Bethesda, MD 20894, Web Policies Review of the correlation between blood flow velocity and polycythemia in the fetus, neonate and adult: appropriate diagnostic levels need to be determined for twin anemia-polycythemia sequence. 7 0 obj mca doppler fetal cerebral artery middle anemia ob technique proximal occupies enlarge obimages Cerebral vasoconstriction causing decrease in arterial flow may have role. In the latter model, ba-PWV retained significance, whereas cf-PWV did not. OH: substantial conception and design of the paper, the acquisition, analysis, and interpretation of data for the paper.
Hypertension was a blood pressure of 140 mm Hg systolic or 90 mm Hg diastolic or higher. An association with HICS, lacrimation, and the pronounced increase in MFV and decrease in RI indicates that vascular changes are important in the pathogeneses of this phenomenon. 9. Copyright 2019 Hensel, Burow, Mages, Wienke, Kraya and Zierz. 10:677. doi: 10.3389/fneur.2019.00677. endobj This may indicate an involvement of the trigeminal-parasympathetic vasodilator reflex. The present study must be interpreted within the context of some potential limitations. Univariate analyses between PI and each of the arterial stiffness measures were performed. Umbilical artery peak systolic velocity measurements for prediction of perinatal outcome among IUGR fetuses.
(2018) 38:1211. 8600 Rockville Pike Validated oscillometric SpaceLabs 90217 monitors (SpaceLabs, Redmont, WA) were programmed to obtain blood pressure readings at 20-min intervals from 6:00 AM until 10:00 PM and at 30-min intervals from 10:00 PM to 6:00 AM.15 All recordings covered >20 h and included at least 10 readings during the awakening period and five readings during sleep. HHS Vulnerability Disclosure, Help In single regression analysis, the PI increased with age (r = 0.25; P < 0.001), but was not correlated with body mass index (r = 0.05; P = 0.36). In volunteers without provoked HICS, MFV was higher in volunteers with a positive HICS history than in volunteers with a negative HICS history (Table 1). Using the Omron Colin BP-203RPEIII VP-1000 device (Omron Health Care, Kyoto, Japan) ba-PWV was measured as described previously.13 The Omron Colin device extrapolates the travel path from body height and automatically computes ba-PWV by dividing time difference between the pulse waves that were transmitted to the brachial and ankle arteries by the travel path.13. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. official website and that any information you provide is encrypted We measured the MCA pulsatility index (PI) by transcranial Doppler ultrasonography.
SZ: substantial conception and design of the paper, interpretation of the data for the paper, and revising it critically for important intellectual content. Participants wore light indoor clothing without shoes for body weight measurement. We hypothesized that the flow pattern in the MCA would reflect the pulsatile component of systemic blood pressure, which in turn is related to arterial stiffness. In order to assess confounding factors, the volunteers were told to drink 200 ml of luke-warm water (temperature 22 2C) as fast as possible. endstream elevation (4 m/s) in aortic PWV was associated with a 39% higher risk of fatal stroke. (2015) 2:00067. doi: 10.15406/jnsk.2015.02.00067, Keywords: ice cream headache, ingestion of cold stimuli, mean flow velocity, cerebrovascular resistance, trigeminal-parasympathetic vasodilator reflex, Citation: Hensel O, Burow P, Mages S, Wienke A, Kraya T and Zierz S (2019) Increased Blood Flow Velocity in Middle Cerebral Artery and Headache Upon Ingestion of Ice Water. x+ | All subjects gave written informed consent in accordance with the Declaration of Helsinki. The site is secure. Sleigh JW. The end of the stimulation period was defined as the last five heartbeats before and after drinking stopped (Figure 1). endstream Brown CM, Sanya EO, Hilz MJ. In volunteers with HICS and lacrimation, the increase in MFV was even more pronounced than in volunteers with HICS but without lacrimation (12.8 11.3 vs. 5.9 9.9%, p = 0.006; Figure 2). Epub 2015 Sep 7. The heart rate (HR) and RMSSD (root mean square of successive differences: parasympathetic influence on heart rate variability) was calculated from the time between two systolic peaks and averaged for resting and end of stimulation period. The data on changes in MFV in the MCA induced by the ingestion of cold stimuli are inconsistent. We considered the following covariables: sex, age, body mass index, current smoking and alcohol intake, plasma glucose, serum total cholesterol, heart rate, and mean arterial pressure. endstream Compared to men (Table 1), women had faster mean blood flow velocity at MCA (68.0 15.0 vs. 58.3 14.7 cm/s; P < 0.001) but lower PI (75.4 11.0 vs. 82.3 15.0; P < 0.001). 2016 Feb;47(2):152-7. doi: 10.1002/uog.14782. Front. A self-programmed procedure detected the end-diastolic velocity and the peak-systolic velocity in the envelope, and calculated the MFV and RI in both MCAs. % With the patient in the supine position, the ultrasonographer recorded end-diastolic (Vd), peak systolic (Vs), and mean (Vm) blood flow velocities in both MCAs at a depth of 50 mm (4555 mm). <>stream Keywords: Start and end of ingestion and headache was marked in the recording. (2016) 263:110610. The international classification of headache disorders, 3rd edition. Mumford JM. *Correspondence: Ole Hensel, ole.hensel@medizin.uni-halle.de, https://www.fasebj.org/doi/abs/10.1096/fasebj.26.1_supplement.685.4, Creative Commons Attribution License (CC BY). Study protocol: The velocity envelope of both middle cerebral arteries was continuously recorded. Brandts et al.5 demonstrated a significant association between the odds ratio of lacunar brain infarcts and PWV in the aortic arch, independent of sex, age, and hypertension duration. Ingestion of ice water stimulates cold receptors of the trigeminal (V2, V3), glossopharyngeal and vagus nerves. In models including both cf-PWV and ba-PWV, only the latter was significant (0.19%; P = 0.84 vs. +3.54%; P < 0.001). 1 Our current findings might have clinical implications. A middle cerebral artery peak systolic velocity value (MCA-PSV) persistently greater than 1.5 times the median of the normal population is utilized to detect moderate and severe anemia in fetuses at risk. Would you like email updates of new search results?
27.Paulson OB, Waldemar G, Schmidt JF, Strandgaard S. 28.Hirata K, Yaginuma T, O'Rourke MF, Kawakami M. 29.Kelly R, Hayward C, Avolio A, O'Rourke M. Oxford University Press is a department of the University of Oxford. 3 0 obj The variance of PI was mainly explained by pulse pressure measures (3967% of total variance), and was very little explained by ba-PWV (5%). These observations suggest that brain arteries are subjected to high pulsatile circumferential stress and high longitudinal shear stress. No use, distribution or reproduction is permitted which does not comply with these terms. For database management and statistical analyses, we used the SAS software, version 9.1.3 (SAS Institute, Cary, NC). (2012) 32:112330.
University of Erlangen Nuremberg, Germany, Faculty of Medicine, Okan University, Turkey. 1 PWV was the distance in meters divided by the transit time in seconds. 6.Maldonado J, Pereira T, Polnia J, Silva JA, Morais J, Marques M. 7.Kim DH, Choi JH, Moon JS, Kim HJ, Cha JK. Forehead stimulation decreases volume of the infarction triggered by permanent occlusion of middle cerebral artery in rats. FASEB J. In a further step of the analysis, we constructed a model including both bPP and ba-PWV in addition to the covariables. endstream The cold stimulation of the trigeminal nerve might also activate the sympathetic system, which causes peripheral vasoconstriction, a lowering of skin temperature (8) and increase in MAP (9). Within 1 week before the arterial examinations, the patients underwent 24-h ambulatory blood pressure monitoring. Few studies addressed the relation between the flow pattern in cerebral artery and arterial stiffness in the systemic circulation. The correlations between the PI and brain lesions were 0.52 (P < 0.001) for periventricular hyperintensity, 0.54 (P < 0.001) for deep white matter hyperintensity and 0.31 (P = 0.02) for lacunar disease. From March 2009 to January 2011, we invited 791 consecutive patients who were not on antihypertensive medications for at least 2 weeks and were referred for ambulatory blood pressure monitoring to the Hypertension Clinic of Ruijin Hospital, Shanghai, China. Cephalalgia. Bethesda, MD 20894, Web Policies Review of the correlation between blood flow velocity and polycythemia in the fetus, neonate and adult: appropriate diagnostic levels need to be determined for twin anemia-polycythemia sequence. 7 0 obj mca doppler fetal cerebral artery middle anemia ob technique proximal occupies enlarge obimages Cerebral vasoconstriction causing decrease in arterial flow may have role. In the latter model, ba-PWV retained significance, whereas cf-PWV did not. OH: substantial conception and design of the paper, the acquisition, analysis, and interpretation of data for the paper. Hypertension was a blood pressure of 140 mm Hg systolic or 90 mm Hg diastolic or higher. An association with HICS, lacrimation, and the pronounced increase in MFV and decrease in RI indicates that vascular changes are important in the pathogeneses of this phenomenon. 9. Copyright 2019 Hensel, Burow, Mages, Wienke, Kraya and Zierz. 10:677. doi: 10.3389/fneur.2019.00677. endobj This may indicate an involvement of the trigeminal-parasympathetic vasodilator reflex. The present study must be interpreted within the context of some potential limitations. Univariate analyses between PI and each of the arterial stiffness measures were performed. Umbilical artery peak systolic velocity measurements for prediction of perinatal outcome among IUGR fetuses.
(2018) 38:1211. 8600 Rockville Pike Validated oscillometric SpaceLabs 90217 monitors (SpaceLabs, Redmont, WA) were programmed to obtain blood pressure readings at 20-min intervals from 6:00 AM until 10:00 PM and at 30-min intervals from 10:00 PM to 6:00 AM.15 All recordings covered >20 h and included at least 10 readings during the awakening period and five readings during sleep. HHS Vulnerability Disclosure, Help In single regression analysis, the PI increased with age (r = 0.25; P < 0.001), but was not correlated with body mass index (r = 0.05; P = 0.36). In volunteers without provoked HICS, MFV was higher in volunteers with a positive HICS history than in volunteers with a negative HICS history (Table 1). Using the Omron Colin BP-203RPEIII VP-1000 device (Omron Health Care, Kyoto, Japan) ba-PWV was measured as described previously.13 The Omron Colin device extrapolates the travel path from body height and automatically computes ba-PWV by dividing time difference between the pulse waves that were transmitted to the brachial and ankle arteries by the travel path.13. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. official website and that any information you provide is encrypted We measured the MCA pulsatility index (PI) by transcranial Doppler ultrasonography.
SZ: substantial conception and design of the paper, interpretation of the data for the paper, and revising it critically for important intellectual content. Participants wore light indoor clothing without shoes for body weight measurement. We hypothesized that the flow pattern in the MCA would reflect the pulsatile component of systemic blood pressure, which in turn is related to arterial stiffness. In order to assess confounding factors, the volunteers were told to drink 200 ml of luke-warm water (temperature 22 2C) as fast as possible. endstream elevation (4 m/s) in aortic PWV was associated with a 39% higher risk of fatal stroke. (2015) 2:00067. doi: 10.15406/jnsk.2015.02.00067, Keywords: ice cream headache, ingestion of cold stimuli, mean flow velocity, cerebrovascular resistance, trigeminal-parasympathetic vasodilator reflex, Citation: Hensel O, Burow P, Mages S, Wienke A, Kraya T and Zierz S (2019) Increased Blood Flow Velocity in Middle Cerebral Artery and Headache Upon Ingestion of Ice Water. x+ | All subjects gave written informed consent in accordance with the Declaration of Helsinki. The site is secure. Sleigh JW. The end of the stimulation period was defined as the last five heartbeats before and after drinking stopped (Figure 1). endstream Brown CM, Sanya EO, Hilz MJ. In volunteers with HICS and lacrimation, the increase in MFV was even more pronounced than in volunteers with HICS but without lacrimation (12.8 11.3 vs. 5.9 9.9%, p = 0.006; Figure 2). Epub 2015 Sep 7. The heart rate (HR) and RMSSD (root mean square of successive differences: parasympathetic influence on heart rate variability) was calculated from the time between two systolic peaks and averaged for resting and end of stimulation period. The data on changes in MFV in the MCA induced by the ingestion of cold stimuli are inconsistent. We considered the following covariables: sex, age, body mass index, current smoking and alcohol intake, plasma glucose, serum total cholesterol, heart rate, and mean arterial pressure. endstream Compared to men (Table 1), women had faster mean blood flow velocity at MCA (68.0 15.0 vs. 58.3 14.7 cm/s; P < 0.001) but lower PI (75.4 11.0 vs. 82.3 15.0; P < 0.001). 2016 Feb;47(2):152-7. doi: 10.1002/uog.14782. Front. A self-programmed procedure detected the end-diastolic velocity and the peak-systolic velocity in the envelope, and calculated the MFV and RI in both MCAs. % With the patient in the supine position, the ultrasonographer recorded end-diastolic (Vd), peak systolic (Vs), and mean (Vm) blood flow velocities in both MCAs at a depth of 50 mm (4555 mm). <>stream Keywords: Start and end of ingestion and headache was marked in the recording. (2016) 263:110610. The international classification of headache disorders, 3rd edition. Mumford JM. *Correspondence: Ole Hensel, ole.hensel@medizin.uni-halle.de, https://www.fasebj.org/doi/abs/10.1096/fasebj.26.1_supplement.685.4, Creative Commons Attribution License (CC BY). Study protocol: The velocity envelope of both middle cerebral arteries was continuously recorded. Brandts et al.5 demonstrated a significant association between the odds ratio of lacunar brain infarcts and PWV in the aortic arch, independent of sex, age, and hypertension duration. Ingestion of ice water stimulates cold receptors of the trigeminal (V2, V3), glossopharyngeal and vagus nerves. In models including both cf-PWV and ba-PWV, only the latter was significant (0.19%; P = 0.84 vs. +3.54%; P < 0.001). 1 Our current findings might have clinical implications. A middle cerebral artery peak systolic velocity value (MCA-PSV) persistently greater than 1.5 times the median of the normal population is utilized to detect moderate and severe anemia in fetuses at risk. Would you like email updates of new search results?